Sunday, 25th June 2017

TWO PHD SCHOLARSHIPS IN “Pre-clinical studies on therapeutic factor delivery in the basal ganglia for PD and HD” and ” Pre-clinical studies on neurotransmitter replacement in the basal ganglia for PD and HD”

Applications are invited from suitably qualified candidates for a position funded by the Marie Skłodowska-Curie project “Training4CRM” (“European Training Network for Cell-based Regenerative Medicine”) within the Horizon 2020 programme of the European Union, starting in October 2017, the latest. The appointment will be on a temporary basis for a maximum period of 3 years (PhD student) and will be placed at the Dept. Molecular Biology, Universidad Autónoma of Madrid (UAM), and Dept. Molecular Neuropathology of the Centre of Molecular Biology Severo Ochoa (CBMSO, CSIC-UAM).

Training4CRM is a four-year project, funded by the European Union Horizon 2020 Programme (H2020-MSCA-ITN-2016) under the Marie Skłodowska-Curie Innovative Training Network (European Training Network) and Grant Agreement No. 722779. The project is highly cross disciplinary and focuses on bridging the existing gaps within Cell-based Regenerative Medicine (CRM) for treatment of neurodegenerative disorders (e.g. Parkinson´s (PD), Huntington´s (HD) Epilepsy (EPI)). The project offers training in transferrable skills and inter-disciplinary research training in micro- and nano-engineering, biotechnology and pre-clinical research, at the highest international level and quality. The Taining4CRM network comprises 6 academic and 3 industrial beneficiaries from 6 European countries (Denmark, Spain, Sweden, Norway, Italy, and the Netherlands). In addition, six other partners, mostly non-academic, will offer secondments and specialised training. The Project Summary can be found at the end of this document.

Two PhD positions (ESRs 12, 13) are available to study either therapeutic factor delivery or neurotransmitter replacement, using cell carrier implants (carbon and polymer scaffolds), in clinically relevant animal models of Parkinson’s and Huntington’s diseases. The microglial and glial reaction of the host to the implants will be studied, alongside the histological migration, survival and integration of the implanted cell-loaded probes. Neurotransmitter release will be optogenetically controlled. Therapeutic effects of the factors and/or neurotransmitters will be studied. Host brain and implant crosstalk will also be studied. [A summary of the thesis projects can be made available upon request].

You can find details of the position in the attached file.